Two of the most significant pieces of legislation in decades, the Patient Protection and Affordable Care Act (ACA) and the Jumpstart Our Business Startups (JOBS) Act, are poised to transform the entire spectrum of health care. The ACA regulates everything from health insurance requirements to tax collection. The JOBS Act regulates businesses that fund their ventures online. In tandem, these two bills have created a new world for health care innovators and investors. Ironically though, it is the innovators and investors who are joining forces to do what the ACA is unable to do: reduce costs and increase access. At the 7th Annual OneMedForum recently in San Francisco more than 400 one-on-one investor meetings were conducted between venture capitalists and startup health care companies, all in the name of disruptive innovation.