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In 1929, just before the stock market crash, Louis Bamberger and his sister, Caroline Bamberger Fuld, sold their department store in Newark to
 R.H. Macy and Company for $25 million ( $343 million in 2015 dollars). Grateful to the people of Newark for their support, they planned to endow a medical college in that city.

Yet when they approached Abraham Flexner, the foremost authority on higher education at the time, he told them that there was little point in building a medical school just across the river from Manhattan, where there was no shortage of medical talent.  Instead, he asked the Bambergers to be more ambitious.